Algorithmic Bias, Fairness, and Safety
Algorithmic bias, stability in diagnostic accuracy
Obra JK, Singh C, Watkins K, Feng J, Obermeyer Z, Kornblith A. Potential for Algorithmic Bias in Clinical Decision Instrument Development. NPJ Digit Med. 2025 Dec 10;8(1):762. doi: 10.1038/s41746-025-02119-7. PMID: 41372566; PMCID: PMC12708808.
Tan YS, Singh C, Nasseri K, Agarwal A, Duncan J, Ronen O, Epland M, Kornblith A, Yu B. Fast interpretable greedy-tree sums. Proc Natl Acad Sci U S A. 2025 Feb 18;122(7):e2310151122. doi: 10.1073/pnas.2310151122. Epub 2025 Feb 14. PMID: 39951504; PMCID: PMC11848335.
Foster AA, Watkins K, Trivedi TK, Cruz-Romero M, Leibovich SA, Daftary RK, Kornblith AE, Grupp-Phelan J, Sporer KA, Kellison C, Glomb NW. Physical restraint use in children with mental and behavioral health emergencies in the prehospital setting. J Am Coll Emerg Physicians Open. 2023 Aug 16;4(4):e13016. doi: 10.1002/emp2.13016. PMID: 37600903; PMCID: PMC10432898.
Clinical Decision Support
Artificial intelligence clinical decision rules, evaluating language models for clinical trials and care
Williams CYK, Miao BY, Kornblith AE, Butte AJ. Evaluating the use of large language models to provide clinical recommendations in the Emergency Department. Nat Commun. 2024 Oct 8;15(1):8236. doi: 10.1038/s41467-024-52415-1. PMID: 39379357; PMCID: PMC11461960.
Williams CYK, Zack T, Miao BY, Sushil M, Wang M, Kornblith AE, Butte AJ. Use of a large language model to assess clinical acuity of adults in the emergency department. JAMA Netw Open. 2024 May 1;7(5):e248895. doi: 10.1001/jamanetworkopen.2024.8895. PMID: 38713466; PMCID: PMC11077390.
Kornblith AE, Addo N, Dong R, Rogers R, Grupp-Phelan J, Butte A, Gupta P, Callcut RA, Arnaout R. Development and validation of a deep learning strategy for automated view classification of pediatric focused assessment with sonography for trauma. J Ultrasound Med. 2022 Aug;41(8):1915-1924. doi: 10.1002/jum.15868. Epub 2021 Nov 6. PMID: 34741469; PMCID: PMC9072593.
Clinical Trials
Sperry JL, Guyette FX, Rosario-Rivera BL, Kutcher ME, Kornblith LZ, Cotton BA, Wilson CT, Inaba K, Zadorozny EV, Vincent LE, Harner AM, Love ET, Doherty JE, Cuschieri J, Kornblith AE, Fox EE, Bai Y, Hoffman MK, Seger CP, Hudgins J, Mallett-Smith S, Neal MD, Leeper CM, Spinella PC, Yazer MH, Wisniewski SR; Cold Stored Platelet for Hemorrhagic Shock (CRISP-HS) Study Group. Early Cold Stored Platelet Transfusion Following Severe Injury: A Randomized Clinical Trial. Ann Surg. 2024 Aug 1;280(2):212-221. doi: 10.1097/SLA.0000000000006317. Epub 2024 May 6. PMID: 38708880; PMCID: PMC11224567.
Informatics & Infrastructure
Data pipelines, annotation frameworks, and electronic health record integration
Sun L, Agarwal A, Kornblith A, Yu B, Xiong C. ED-Copilot: Reduce Emergency Department Wait Time with Language Model Diagnostic Assistance. arXiv. Published online 2024. arXiv:2402.13448. doi:10.48550/arXiv.2402.13448
Student-Led Projects
Bains JK, Williams CYK, Johnson D, Schwartz H, Sabbineni N, Butte AJ, Kornblith AE. Enhancing emergency department charting: Using Generative Pre-trained Transformer-4 (GPT-4) to identify laceration repairs. Acad Emerg Med. 2025 Jan;32(1):94-97. doi: 10.1111/acem.14995. Epub 2024 Jul 31. PMID: 39082468; PMCID: PMC11726143.
Yusuf HM, Rosenthal E, Kornblith A, Sowar C, Del Toro R, Chen CC. Understanding a community's needs for an emergency department-based childhood injury prevention programme: a mixed-methods study. Inj Prev. 2024 May 20;30(3):200-205. doi: 10.1136/ip-2023-044920. PMID: 38050122.
Devlin G, Addo N, Shaahinfar A, Chen CC, Grupp-Phelan J, Kornblith AE. Toxic exposures among young children one year into the COVID-19 pandemic: a retrospective review of three San Francisco Bay Area emergency departments. J Emerg Med. 2023 Feb;64(2):263-268. doi: 10.1016/j.jemermed.2022.09.035. Epub 2022 Sep 19. PMID: 36828751; PMCID: PMC9482847.
Thought Leadership
Op-eds, commentary, research letters, and methodological critiques
Lin-Martore M, Kornblith A, Firnberg M, Haque A, O'Brien B. Trust of artificial intelligence-augmented point-of-care ultrasound among pediatric emergency physicians. J Am Coll Emerg Physicians Open. 2025 Jun 5;6(4):100173. doi: 10.1016/j.acepjo.2025.100173. PMID: 40528866; PMCID: PMC12172972.
Kornblith A, Grupp-Phelan J. Lessons from the runway: how airline operational crashes illuminate the ED’s technical debt problem. SAEM Pulse. November–December 2024:90-93.
Trauma Diagnostics
Deep learning, image segmentation, trauma and imaging diagnostics
Firnberg M, Addo N, Lin-Martore M, Shaahinfar A, Kornblith A. Evaluation of Focused Assessment With Sonography for Trauma Completeness of Children in the Clinical Setting. J Ultrasound Med. 2024 May;43(5):873-879. doi: 10.1002/jum.16417. Epub 2024 Jan 28. PMID: 38282464; PMCID: PMC11335411.
Shaahinfar A, Wiebelhaus JR, Addo N, Cohen RA, Karakas-Rothey P, Kornblith AE. Reliability of Physician Estimation of Pelvic Free Fluid Volume on the Pediatric Focused Assessment With Sonography for Trauma. J Ultrasound Med. 2025 Jun;44(6):1017-1025. doi: 10.1002/jum.16661. Epub 2025 Feb 13. PMID: 39945112; PMCID: PMC12067152.
Grade MM, Ehlers PF, Kornblith AE, Mower WR, Raja AS, Schleifer J, Liteplo A, Rodriguez RM. Effect of the extended focused assessment with sonography for trauma on the screening performance of the National Emergency X-Radiography Utilization Study Chest Decision Instrument. Ann Emerg Med. 2023 Apr;81(4):495-500. doi: 10.1016/j.annemergmed.2022.09.027. Epub 2023 Feb 7. PMID: 36754698.
Kornblith AE, Singh C, Devlin G, Addo N, Streck CJ, Holmes JF, Kuppermann N, Grupp-Phelan J, Fineman J, Butte AJ, Yu B. Predictability and stability testing to assess clinical decision instrument performance for children after blunt torso trauma. PLOS Digit Health. 2022 Aug 8;1(8):e0000076. doi: 10.1371/journal.pdig.0000076. PMID: 36812570; PMCID: PMC9931266.
Kornblith AE, Addo N, Plasencia M, Shaahinfar A, Lin-Martore M, Sabbineni N, Gold D, Bellman L, Berant R, Bergmann KR, Brenkert TE, Chen A, Constantine E, Deanehan JK, Dessie A, Elkhunovich M, Fischer J, Gravel CA, Kharasch S, Kwan CW, Lam SHF, Neal JT, Pade KH, Rempell R, Shefrin AE, Sivitz A, Snelling PJ, Tessaro MO, White W. Development of a consensus-based definition of focused assessment with sonography for trauma in children. JAMA Netw Open. 2022 Mar 1;5(3):e222922. doi: 10.1001/jamanetworkopen.2022.2922. PMID: 35302632; PMCID: PMC8933745.